Diupres
Brand names,
Diupres
Analogs
Diupres
Brand Names Mixture
- Hydropres 25 Tab (Hydrochlorothiazide + Reserpine)
- Hydropres 50 Tab (Hydrochlorothiazide + Reserpine)
- SER-AP-ES Tab (Hydralazine Hydrochloride + Hydrochlorothiazide + Reserpine)
Diupres
Chemical_Formula
C33H40N2O9
Diupres
RX_link
No information avaliable
Diupres
fda sheet
Diupres
msds (material safety sheet)
Diupres
Synthesis Reference
No information avaliable
Diupres
Molecular Weight
608.679 g/mol
Diupres
Melting Point
264.5 oC
Diupres
H2O Solubility
73 mg/L
Diupres
State
Solid
Diupres
LogP
3.32
Diupres
Dosage Forms
Tablets
Diupres
Indication
Foe the treatment of hypertension
Diupres
Pharmacology
Reserpine is an adrenergic blocking agent used to treat mild to moderate hypertension via the disruption of norepinephrine vesicular storage. The antihypertensive actions of Reserpine are a result of its ability to deplete catecholamines from peripheral sympathetic nerve endings. These substances are normally involved in controlling heart rate, force of cardiac contraction and peripheral resistance.
Diupres
Absorption
No information avaliable
Diupres
side effects and Toxicity
Possible human carcinogen. May cause reproductive harm. ORL-RAT LD50 420 mg/kg; IPR-RAT LD50 44 mg/kg; IVN-RAT LD50 15 mg/kg; ORL-MUS LD50 200 mg/kg; SCU-MUS LD50 52 mg/kg; IPR-RBT LD50 7 mg/kg
Diupres
Patient Information
No information avaliable
Diupres
Organisms Affected
Humans and other mammals