Cetirizine
Brand names,
Cetirizine
Analogs
Cetirizine
Brand Names Mixture
Cetirizine
Chemical_Formula
C21H25ClN2O3
Cetirizine
RX_link
http://www.rxlist.com/cgi/generic/cetiriz.htm
Cetirizine
fda sheet
Cetirizine
msds (material safety sheet)
Cetirizine
Synthesis Reference
E. Baltes et al., U.S. Pat. 4,525,358 (1985)
Cetirizine
Molecular Weight
388.888 g/mol
Cetirizine
Melting Point
110-115oC
Cetirizine
H2O Solubility
101 mg/L
Cetirizine
State
solid
Cetirizine
LogP
3.238
Cetirizine
Dosage Forms
Tablets
Cetirizine
Indication
For the relief of symptoms associated with seasonal allergic rhinitis, perennial allergic rhinitis and the treatment of the uncomplicated skin manifestations of chronic idiopathic urticaria
Cetirizine
Pharmacology
Cetirizine, the active metabolite of the piperazine H1-receptor antagonist hydroxyzine, is used to treat chronic idiopathic urticaria, perennial allergic rhinitis, seasonal allergic rhinitis, allergic asthma, physical urticaria, and atopic dermatitis.
Cetirizine
Absorption
mean peak plasma concentration (Cmax) of 114 ng/mL at a time (Tmax) of 2.2 hours postdose was observed for cetirizine
Cetirizine
side effects and Toxicity
Somnolence (sleepiness or unusual drowsiness), restlessness, irritability
Cetirizine
Patient Information
Cetirizine
Organisms Affected
Humans and other mammals