Virlix
Brand names,
Virlix
Analogs
Virlix
Brand Names Mixture
Virlix
Chemical_Formula
C21H25ClN2O3
Virlix
RX_link
http://www.rxlist.com/cgi/generic/cetiriz.htm
Virlix
fda sheet
Virlix
msds (material safety sheet)
Virlix
Synthesis Reference
E. Baltes et al., U.S. Pat. 4,525,358 (1985)
Virlix
Molecular Weight
388.888 g/mol
Virlix
Melting Point
110-115oC
Virlix
H2O Solubility
101 mg/L
Virlix
State
solid
Virlix
LogP
3.238
Virlix
Dosage Forms
Tablets
Virlix
Indication
For the relief of symptoms associated with seasonal allergic rhinitis, perennial allergic rhinitis and the treatment of the uncomplicated skin manifestations of chronic idiopathic urticaria
Virlix
Pharmacology
Cetirizine, the active metabolite of the piperazine H1-receptor antagonist hydroxyzine, is used to treat chronic idiopathic urticaria, perennial allergic rhinitis, seasonal allergic rhinitis, allergic asthma, physical urticaria, and atopic dermatitis.
Virlix
Absorption
mean peak plasma concentration (Cmax) of 114 ng/mL at a time (Tmax) of 2.2 hours postdose was observed for cetirizine
Virlix
side effects and Toxicity
Somnolence (sleepiness or unusual drowsiness), restlessness, irritability
Virlix
Patient Information
Virlix
Organisms Affected
Humans and other mammals