Alerlisin
Brand names,
Alerlisin
Analogs
Alerlisin
Brand Names Mixture
Alerlisin
Chemical_Formula
C21H25ClN2O3
Alerlisin
RX_link
http://www.rxlist.com/cgi/generic/cetiriz.htm
Alerlisin
fda sheet
Alerlisin
msds (material safety sheet)
Alerlisin
Synthesis Reference
E. Baltes et al., U.S. Pat. 4,525,358 (1985)
Alerlisin
Molecular Weight
388.888 g/mol
Alerlisin
Melting Point
110-115oC
Alerlisin
H2O Solubility
101 mg/L
Alerlisin
State
solid
Alerlisin
LogP
3.238
Alerlisin
Dosage Forms
Tablets
Alerlisin
Indication
For the relief of symptoms associated with seasonal allergic rhinitis, perennial allergic rhinitis and the treatment of the uncomplicated skin manifestations of chronic idiopathic urticaria
Alerlisin
Pharmacology
Cetirizine, the active metabolite of the piperazine H1-receptor antagonist hydroxyzine, is used to treat chronic idiopathic urticaria, perennial allergic rhinitis, seasonal allergic rhinitis, allergic asthma, physical urticaria, and atopic dermatitis.
Alerlisin
Absorption
mean peak plasma concentration (Cmax) of 114 ng/mL at a time (Tmax) of 2.2 hours postdose was observed for cetirizine
Alerlisin
side effects and Toxicity
Somnolence (sleepiness or unusual drowsiness), restlessness, irritability
Alerlisin
Patient Information
Alerlisin
Organisms Affected
Humans and other mammals