Cetirizinum [Latin]
Brand names,
Cetirizinum [Latin]
Analogs
Cetirizinum [Latin]
Brand Names Mixture
Cetirizinum [Latin]
Chemical_Formula
C21H25ClN2O3
Cetirizinum [Latin]
RX_link
http://www.rxlist.com/cgi/generic/cetiriz.htm
Cetirizinum [Latin]
fda sheet
Cetirizinum [Latin]
msds (material safety sheet)
Cetirizinum [Latin]
Synthesis Reference
E. Baltes et al., U.S. Pat. 4,525,358 (1985)
Cetirizinum [Latin]
Molecular Weight
388.888 g/mol
Cetirizinum [Latin]
Melting Point
110-115oC
Cetirizinum [Latin]
H2O Solubility
101 mg/L
Cetirizinum [Latin]
State
solid
Cetirizinum [Latin]
LogP
3.238
Cetirizinum [Latin]
Dosage Forms
Tablets
Cetirizinum [Latin]
Indication
For the relief of symptoms associated with seasonal allergic rhinitis, perennial allergic rhinitis and the treatment of the uncomplicated skin manifestations of chronic idiopathic urticaria
Cetirizinum [Latin]
Pharmacology
Cetirizine, the active metabolite of the piperazine H1-receptor antagonist hydroxyzine, is used to treat chronic idiopathic urticaria, perennial allergic rhinitis, seasonal allergic rhinitis, allergic asthma, physical urticaria, and atopic dermatitis.
Cetirizinum [Latin]
Absorption
mean peak plasma concentration (Cmax) of 114 ng/mL at a time (Tmax) of 2.2 hours postdose was observed for cetirizine
Cetirizinum [Latin]
side effects and Toxicity
Somnolence (sleepiness or unusual drowsiness), restlessness, irritability
Cetirizinum [Latin]
Patient Information
Cetirizinum [Latin]
Organisms Affected
Humans and other mammals