Zyrtec
Brand names,
Zyrtec
Analogs
Zyrtec
Brand Names Mixture
Zyrtec
Chemical_Formula
C21H25ClN2O3
Zyrtec
RX_link
http://www.rxlist.com/cgi/generic/cetiriz.htm
Zyrtec
fda sheet
Zyrtec
msds (material safety sheet)
Zyrtec
Synthesis Reference
E. Baltes et al., U.S. Pat. 4,525,358 (1985)
Zyrtec
Molecular Weight
388.888 g/mol
Zyrtec
Melting Point
110-115oC
Zyrtec
H2O Solubility
101 mg/L
Zyrtec
State
solid
Zyrtec
LogP
3.238
Zyrtec
Dosage Forms
Tablets
Zyrtec
Indication
For the relief of symptoms associated with seasonal allergic rhinitis, perennial allergic rhinitis and the treatment of the uncomplicated skin manifestations of chronic idiopathic urticaria
Zyrtec
Pharmacology
Cetirizine, the active metabolite of the piperazine H1-receptor antagonist hydroxyzine, is used to treat chronic idiopathic urticaria, perennial allergic rhinitis, seasonal allergic rhinitis, allergic asthma, physical urticaria, and atopic dermatitis.
Zyrtec
Absorption
mean peak plasma concentration (Cmax) of 114 ng/mL at a time (Tmax) of 2.2 hours postdose was observed for cetirizine
Zyrtec
side effects and Toxicity
Somnolence (sleepiness or unusual drowsiness), restlessness, irritability
Zyrtec
Patient Information
Zyrtec
Organisms Affected
Humans and other mammals