Setir
Brand names,
Setir
Analogs
Setir
Brand Names Mixture
Setir
Chemical_Formula
C21H25ClN2O3
Setir
RX_link
http://www.rxlist.com/cgi/generic/cetiriz.htm
Setir
fda sheet
Setir
msds (material safety sheet)
Setir
Synthesis Reference
E. Baltes et al., U.S. Pat. 4,525,358 (1985)
Setir
Molecular Weight
388.888 g/mol
Setir
Melting Point
110-115oC
Setir
H2O Solubility
101 mg/L
Setir
State
solid
Setir
LogP
3.238
Setir
Dosage Forms
Tablets
Setir
Indication
For the relief of symptoms associated with seasonal allergic rhinitis, perennial allergic rhinitis and the treatment of the uncomplicated skin manifestations of chronic idiopathic urticaria
Setir
Pharmacology
Cetirizine, the active metabolite of the piperazine H1-receptor antagonist hydroxyzine, is used to treat chronic idiopathic urticaria, perennial allergic rhinitis, seasonal allergic rhinitis, allergic asthma, physical urticaria, and atopic dermatitis.
Setir
Absorption
mean peak plasma concentration (Cmax) of 114 ng/mL at a time (Tmax) of 2.2 hours postdose was observed for cetirizine
Setir
side effects and Toxicity
Somnolence (sleepiness or unusual drowsiness), restlessness, irritability
Setir
Patient Information
Setir
Organisms Affected
Humans and other mammals