Formistin
Brand names,
Formistin
Analogs
Formistin
Brand Names Mixture
Formistin
Chemical_Formula
C21H25ClN2O3
Formistin
RX_link
http://www.rxlist.com/cgi/generic/cetiriz.htm
Formistin
fda sheet
Formistin
msds (material safety sheet)
Formistin
Synthesis Reference
E. Baltes et al., U.S. Pat. 4,525,358 (1985)
Formistin
Molecular Weight
388.888 g/mol
Formistin
Melting Point
110-115oC
Formistin
H2O Solubility
101 mg/L
Formistin
State
solid
Formistin
LogP
3.238
Formistin
Dosage Forms
Tablets
Formistin
Indication
For the relief of symptoms associated with seasonal allergic rhinitis, perennial allergic rhinitis and the treatment of the uncomplicated skin manifestations of chronic idiopathic urticaria
Formistin
Pharmacology
Cetirizine, the active metabolite of the piperazine H1-receptor antagonist hydroxyzine, is used to treat chronic idiopathic urticaria, perennial allergic rhinitis, seasonal allergic rhinitis, allergic asthma, physical urticaria, and atopic dermatitis.
Formistin
Absorption
mean peak plasma concentration (Cmax) of 114 ng/mL at a time (Tmax) of 2.2 hours postdose was observed for cetirizine
Formistin
side effects and Toxicity
Somnolence (sleepiness or unusual drowsiness), restlessness, irritability
Formistin
Patient Information
Formistin
Organisms Affected
Humans and other mammals