Cetirizina [Spanish]
Brand names,
Cetirizina [Spanish]
Analogs
Cetirizina [Spanish]
Brand Names Mixture
Cetirizina [Spanish]
Chemical_Formula
C21H25ClN2O3
Cetirizina [Spanish]
RX_link
http://www.rxlist.com/cgi/generic/cetiriz.htm
Cetirizina [Spanish]
fda sheet
Cetirizina [Spanish]
msds (material safety sheet)
Cetirizina [Spanish]
Synthesis Reference
E. Baltes et al., U.S. Pat. 4,525,358 (1985)
Cetirizina [Spanish]
Molecular Weight
388.888 g/mol
Cetirizina [Spanish]
Melting Point
110-115oC
Cetirizina [Spanish]
H2O Solubility
101 mg/L
Cetirizina [Spanish]
State
solid
Cetirizina [Spanish]
LogP
3.238
Cetirizina [Spanish]
Dosage Forms
Tablets
Cetirizina [Spanish]
Indication
For the relief of symptoms associated with seasonal allergic rhinitis, perennial allergic rhinitis and the treatment of the uncomplicated skin manifestations of chronic idiopathic urticaria
Cetirizina [Spanish]
Pharmacology
Cetirizine, the active metabolite of the piperazine H1-receptor antagonist hydroxyzine, is used to treat chronic idiopathic urticaria, perennial allergic rhinitis, seasonal allergic rhinitis, allergic asthma, physical urticaria, and atopic dermatitis.
Cetirizina [Spanish]
Absorption
mean peak plasma concentration (Cmax) of 114 ng/mL at a time (Tmax) of 2.2 hours postdose was observed for cetirizine
Cetirizina [Spanish]
side effects and Toxicity
Somnolence (sleepiness or unusual drowsiness), restlessness, irritability
Cetirizina [Spanish]
Patient Information
Cetirizina [Spanish]
Organisms Affected
Humans and other mammals