Zyrlex
Brand names,
Zyrlex
Analogs
Zyrlex
Brand Names Mixture
Zyrlex
Chemical_Formula
C21H25ClN2O3
Zyrlex
RX_link
http://www.rxlist.com/cgi/generic/cetiriz.htm
Zyrlex
fda sheet
Zyrlex
msds (material safety sheet)
Zyrlex
Synthesis Reference
E. Baltes et al., U.S. Pat. 4,525,358 (1985)
Zyrlex
Molecular Weight
388.888 g/mol
Zyrlex
Melting Point
110-115oC
Zyrlex
H2O Solubility
101 mg/L
Zyrlex
State
solid
Zyrlex
LogP
3.238
Zyrlex
Dosage Forms
Tablets
Zyrlex
Indication
For the relief of symptoms associated with seasonal allergic rhinitis, perennial allergic rhinitis and the treatment of the uncomplicated skin manifestations of chronic idiopathic urticaria
Zyrlex
Pharmacology
Cetirizine, the active metabolite of the piperazine H1-receptor antagonist hydroxyzine, is used to treat chronic idiopathic urticaria, perennial allergic rhinitis, seasonal allergic rhinitis, allergic asthma, physical urticaria, and atopic dermatitis.
Zyrlex
Absorption
mean peak plasma concentration (Cmax) of 114 ng/mL at a time (Tmax) of 2.2 hours postdose was observed for cetirizine
Zyrlex
side effects and Toxicity
Somnolence (sleepiness or unusual drowsiness), restlessness, irritability
Zyrlex
Patient Information
Zyrlex
Organisms Affected
Humans and other mammals