Cetrizine Hcl
Brand names,
Cetrizine Hcl
Analogs
Cetrizine Hcl
Brand Names Mixture
Cetrizine Hcl
Chemical_Formula
C21H25ClN2O3
Cetrizine Hcl
RX_link
http://www.rxlist.com/cgi/generic/cetiriz.htm
Cetrizine Hcl
fda sheet
Cetrizine Hcl
msds (material safety sheet)
Cetrizine Hcl
Synthesis Reference
E. Baltes et al., U.S. Pat. 4,525,358 (1985)
Cetrizine Hcl
Molecular Weight
388.888 g/mol
Cetrizine Hcl
Melting Point
110-115oC
Cetrizine Hcl
H2O Solubility
101 mg/L
Cetrizine Hcl
State
solid
Cetrizine Hcl
LogP
3.238
Cetrizine Hcl
Dosage Forms
Tablets
Cetrizine Hcl
Indication
For the relief of symptoms associated with seasonal allergic rhinitis, perennial allergic rhinitis and the treatment of the uncomplicated skin manifestations of chronic idiopathic urticaria
Cetrizine Hcl
Pharmacology
Cetirizine, the active metabolite of the piperazine H1-receptor antagonist hydroxyzine, is used to treat chronic idiopathic urticaria, perennial allergic rhinitis, seasonal allergic rhinitis, allergic asthma, physical urticaria, and atopic dermatitis.
Cetrizine Hcl
Absorption
mean peak plasma concentration (Cmax) of 114 ng/mL at a time (Tmax) of 2.2 hours postdose was observed for cetirizine
Cetrizine Hcl
side effects and Toxicity
Somnolence (sleepiness or unusual drowsiness), restlessness, irritability
Cetrizine Hcl
Patient Information
Cetrizine Hcl
Organisms Affected
Humans and other mammals