Apurin
Brand names,
Apurin
Analogs
Apurin
Brand Names Mixture
Apurin
Chemical_Formula
C13H19NO4S
Apurin
RX_link
http://www.rxlist.com/cgi/generic/colbenemid.htm
Apurin
fda sheet
Apurin
msds (material safety sheet)
Apurin
Synthesis Reference
No information avaliable
Apurin
Molecular Weight
285.36 g/mol
Apurin
Melting Point
195 oC
Apurin
H2O Solubility
27.1 mg/L
Apurin
State
Solid
Apurin
LogP
2.324
Apurin
Dosage Forms
Tablet
Apurin
Indication
For the treatment of gout and high levels of uric acid in the blood
Apurin
Pharmacology
Probenecid is a uricosuric and renal tubular blocking agent and is used in combination with colchicine to treat chronic gouty arthritis when complicated by frequent, recurrent acute attacks of gout. It inhibits the tubular reabsorption of urate, thus increasing the urinary excretion of uric acid and decreasing serum urate levels. Effective uricosuria reduces the miscible urate pool, retards urate deposition, and promotes resorption of urate deposits.
Apurin
Absorption
No information avaliable
Apurin
side effects and Toxicity
No information avaliable
Apurin
Patient Information
No information avaliable
Apurin
Organisms Affected
Humans and other mammals