Acetohexamide
Acetohexamide Brand names, Acetohexamide Analogs
Acetohexamide Brand Names Mixture
- No information avaliable
Acetohexamide Chemical_Formula
C15H20N2O4S
Acetohexamide RX_link
No information avaliable
Acetohexamide fda sheet
Acetohexamide msds (material safety sheet)
Acetohexamide Synthesis Reference
No information avaliable
Acetohexamide Molecular Weight
324.396 g/mol
Acetohexamide Melting Point
188-190 oC
Acetohexamide H2O Solubility
3430 mg/L
Acetohexamide State
Solid
Acetohexamide LogP
2.954
Acetohexamide Dosage Forms
Tablet (250, 500 mg)
Acetohexamide Indication
Used in the management of diabetes mellitus type 2 (adult-onset).
Acetohexamide Pharmacology
Acetohexamide is an intermediate-acting, first-generation oral sulfonylurea. It lowers blood sugar by stimulating the pancreatic beta cells to secrete insulin and by helping the body use insulin efficiently. The pancreas must produce insulin for this medication to work. Acetohexamide has one-third the potency of chlorpropamide, and twice the potency of tolbutamide; however, similar hypoglycemic efficacy occurs with equipotent dosage of sulfonylureas.
Acetohexamide Absorption
Rapidly absorbed from the GI tract.
Acetohexamide side effects and Toxicity
Oral, rat LD50: 5 gm/kg; Oral, mouse LD50: >2500 mg/kg. Symptoms of an acetohexamide overdose include hunger, nausea, anxiety, cold sweats, weakness, drowsiness, unconsciousness, and coma.
Acetohexamide Patient Information
No information avaliable
Acetohexamide Organisms Affected
Humans and other mammals
