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Acetohexamidum [INN-Latin] en es it fr

Acetohexamidum [INN-Latin] Brand names, Acetohexamidum [INN-Latin] Analogs

Acetohexamidum [INN-Latin] Brand Names Mixture

  • No information avaliable

Acetohexamidum [INN-Latin] Chemical_Formula

C15H20N2O4S

Acetohexamidum [INN-Latin] RX_link

No information avaliable

Acetohexamidum [INN-Latin] fda sheet

Acetohexamidum [INN-Latin] msds (material safety sheet)

Acetohexamidum_[INN-Latin] MSDS

Acetohexamidum [INN-Latin] Synthesis Reference

No information avaliable

Acetohexamidum [INN-Latin] Molecular Weight

324.396 g/mol

Acetohexamidum [INN-Latin] Melting Point

188-190 oC

Acetohexamidum [INN-Latin] H2O Solubility

3430 mg/L

Acetohexamidum [INN-Latin] State

Solid

Acetohexamidum [INN-Latin] LogP

2.954

Acetohexamidum [INN-Latin] Dosage Forms

Tablet (250, 500 mg)

Acetohexamidum [INN-Latin] Indication

Used in the management of diabetes mellitus type 2 (adult-onset).

Acetohexamidum [INN-Latin] Pharmacology

Acetohexamide is an intermediate-acting, first-generation oral sulfonylurea. It lowers blood sugar by stimulating the pancreatic beta cells to secrete insulin and by helping the body use insulin efficiently. The pancreas must produce insulin for this medication to work. Acetohexamide has one-third the potency of chlorpropamide, and twice the potency of tolbutamide; however, similar hypoglycemic efficacy occurs with equipotent dosage of sulfonylureas.

Acetohexamidum [INN-Latin] Absorption

Rapidly absorbed from the GI tract.

Acetohexamidum [INN-Latin] side effects and Toxicity

Oral, rat LD50: 5 gm/kg; Oral, mouse LD50: >2500 mg/kg. Symptoms of an acetohexamide overdose include hunger, nausea, anxiety, cold sweats, weakness, drowsiness, unconsciousness, and coma.

Acetohexamidum [INN-Latin] Patient Information

No information avaliable

Acetohexamidum [INN-Latin] Organisms Affected

Humans and other mammals