Metaglucina
Metaglucina Brand names, Metaglucina Analogs
Metaglucina Brand Names Mixture
- No information avaliable
Metaglucina Chemical_Formula
C15H20N2O4S
Metaglucina RX_link
No information avaliable
Metaglucina fda sheet
Metaglucina msds (material safety sheet)
Metaglucina Synthesis Reference
No information avaliable
Metaglucina Molecular Weight
324.396 g/mol
Metaglucina Melting Point
188-190 oC
Metaglucina H2O Solubility
3430 mg/L
Metaglucina State
Solid
Metaglucina LogP
2.954
Metaglucina Dosage Forms
Tablet (250, 500 mg)
Metaglucina Indication
Used in the management of diabetes mellitus type 2 (adult-onset).
Metaglucina Pharmacology
Acetohexamide is an intermediate-acting, first-generation oral sulfonylurea. It lowers blood sugar by stimulating the pancreatic beta cells to secrete insulin and by helping the body use insulin efficiently. The pancreas must produce insulin for this medication to work. Acetohexamide has one-third the potency of chlorpropamide, and twice the potency of tolbutamide; however, similar hypoglycemic efficacy occurs with equipotent dosage of sulfonylureas.
Metaglucina Absorption
Rapidly absorbed from the GI tract.
Metaglucina side effects and Toxicity
Oral, rat LD50: 5 gm/kg; Oral, mouse LD50: >2500 mg/kg. Symptoms of an acetohexamide overdose include hunger, nausea, anxiety, cold sweats, weakness, drowsiness, unconsciousness, and coma.
Metaglucina Patient Information
No information avaliable
Metaglucina Organisms Affected
Humans and other mammals
