Cyclamide
Brand names,
Cyclamide
Analogs
Cyclamide
Brand Names Mixture
Cyclamide
Chemical_Formula
C15H20N2O4S
Cyclamide
RX_link
No information avaliable
Cyclamide
fda sheet
Cyclamide
msds (material safety sheet)
Cyclamide
Synthesis Reference
No information avaliable
Cyclamide
Molecular Weight
324.396 g/mol
Cyclamide
Melting Point
188-190 oC
Cyclamide
H2O Solubility
3430 mg/L
Cyclamide
State
Solid
Cyclamide
LogP
2.954
Cyclamide
Dosage Forms
Tablet (250, 500 mg)
Cyclamide
Indication
Used in the management of diabetes mellitus type 2 (adult-onset).
Cyclamide
Pharmacology
Acetohexamide is an intermediate-acting, first-generation oral sulfonylurea. It lowers blood sugar by stimulating the pancreatic beta cells to secrete insulin and by helping the body use insulin efficiently. The pancreas must produce insulin for this medication to work. Acetohexamide has one-third the potency of chlorpropamide, and twice the potency of tolbutamide; however, similar hypoglycemic efficacy occurs with equipotent dosage of sulfonylureas.
Cyclamide
Absorption
Rapidly absorbed from the GI tract.
Cyclamide
side effects and Toxicity
Oral, rat LD50: 5 gm/kg; Oral, mouse LD50: >2500 mg/kg. Symptoms of an acetohexamide overdose include hunger, nausea, anxiety, cold sweats, weakness, drowsiness, unconsciousness, and coma.
Cyclamide
Patient Information
No information avaliable
Cyclamide
Organisms Affected
Humans and other mammals