Dymelor
Brand names,
Dymelor
Analogs
Dymelor
Brand Names Mixture
Dymelor
Chemical_Formula
C15H20N2O4S
Dymelor
RX_link
No information avaliable
Dymelor
fda sheet
Dymelor
msds (material safety sheet)
Dymelor
Synthesis Reference
No information avaliable
Dymelor
Molecular Weight
324.396 g/mol
Dymelor
Melting Point
188-190 oC
Dymelor
H2O Solubility
3430 mg/L
Dymelor
State
Solid
Dymelor
LogP
2.954
Dymelor
Dosage Forms
Tablet (250, 500 mg)
Dymelor
Indication
Used in the management of diabetes mellitus type 2 (adult-onset).
Dymelor
Pharmacology
Acetohexamide is an intermediate-acting, first-generation oral sulfonylurea. It lowers blood sugar by stimulating the pancreatic beta cells to secrete insulin and by helping the body use insulin efficiently. The pancreas must produce insulin for this medication to work. Acetohexamide has one-third the potency of chlorpropamide, and twice the potency of tolbutamide; however, similar hypoglycemic efficacy occurs with equipotent dosage of sulfonylureas.
Dymelor
Absorption
Rapidly absorbed from the GI tract.
Dymelor
side effects and Toxicity
Oral, rat LD50: 5 gm/kg; Oral, mouse LD50: >2500 mg/kg. Symptoms of an acetohexamide overdose include hunger, nausea, anxiety, cold sweats, weakness, drowsiness, unconsciousness, and coma.
Dymelor
Patient Information
No information avaliable
Dymelor
Organisms Affected
Humans and other mammals