Acetohexamid
Acetohexamid Brand names, Acetohexamid Analogs
Acetohexamid Brand Names Mixture
- No information avaliable
Acetohexamid Chemical_Formula
C15H20N2O4S
Acetohexamid RX_link
No information avaliable
Acetohexamid fda sheet
Acetohexamid msds (material safety sheet)
Acetohexamid Synthesis Reference
No information avaliable
Acetohexamid Molecular Weight
324.396 g/mol
Acetohexamid Melting Point
188-190 oC
Acetohexamid H2O Solubility
3430 mg/L
Acetohexamid State
Solid
Acetohexamid LogP
2.954
Acetohexamid Dosage Forms
Tablet (250, 500 mg)
Acetohexamid Indication
Used in the management of diabetes mellitus type 2 (adult-onset).
Acetohexamid Pharmacology
Acetohexamide is an intermediate-acting, first-generation oral sulfonylurea. It lowers blood sugar by stimulating the pancreatic beta cells to secrete insulin and by helping the body use insulin efficiently. The pancreas must produce insulin for this medication to work. Acetohexamide has one-third the potency of chlorpropamide, and twice the potency of tolbutamide; however, similar hypoglycemic efficacy occurs with equipotent dosage of sulfonylureas.
Acetohexamid Absorption
Rapidly absorbed from the GI tract.
Acetohexamid side effects and Toxicity
Oral, rat LD50: 5 gm/kg; Oral, mouse LD50: >2500 mg/kg. Symptoms of an acetohexamide overdose include hunger, nausea, anxiety, cold sweats, weakness, drowsiness, unconsciousness, and coma.
Acetohexamid Patient Information
No information avaliable
Acetohexamid Organisms Affected
Humans and other mammals
