Ordimel
Ordimel Brand names, Ordimel Analogs
Ordimel Brand Names Mixture
- No information avaliable
Ordimel Chemical_Formula
C15H20N2O4S
Ordimel RX_link
No information avaliable
Ordimel fda sheet
Ordimel msds (material safety sheet)
Ordimel Synthesis Reference
No information avaliable
Ordimel Molecular Weight
324.396 g/mol
Ordimel Melting Point
188-190 oC
Ordimel H2O Solubility
3430 mg/L
Ordimel State
Solid
Ordimel LogP
2.954
Ordimel Dosage Forms
Tablet (250, 500 mg)
Ordimel Indication
Used in the management of diabetes mellitus type 2 (adult-onset).
Ordimel Pharmacology
Acetohexamide is an intermediate-acting, first-generation oral sulfonylurea. It lowers blood sugar by stimulating the pancreatic beta cells to secrete insulin and by helping the body use insulin efficiently. The pancreas must produce insulin for this medication to work. Acetohexamide has one-third the potency of chlorpropamide, and twice the potency of tolbutamide; however, similar hypoglycemic efficacy occurs with equipotent dosage of sulfonylureas.
Ordimel Absorption
Rapidly absorbed from the GI tract.
Ordimel side effects and Toxicity
Oral, rat LD50: 5 gm/kg; Oral, mouse LD50: >2500 mg/kg. Symptoms of an acetohexamide overdose include hunger, nausea, anxiety, cold sweats, weakness, drowsiness, unconsciousness, and coma.
Ordimel Patient Information
No information avaliable
Ordimel Organisms Affected
Humans and other mammals
