Gamadiabet
Brand names,
Gamadiabet
Analogs
Gamadiabet
Brand Names Mixture
Gamadiabet
Chemical_Formula
C15H20N2O4S
Gamadiabet
RX_link
No information avaliable
Gamadiabet
fda sheet
Gamadiabet
msds (material safety sheet)
Gamadiabet
Synthesis Reference
No information avaliable
Gamadiabet
Molecular Weight
324.396 g/mol
Gamadiabet
Melting Point
188-190 oC
Gamadiabet
H2O Solubility
3430 mg/L
Gamadiabet
State
Solid
Gamadiabet
LogP
2.954
Gamadiabet
Dosage Forms
Tablet (250, 500 mg)
Gamadiabet
Indication
Used in the management of diabetes mellitus type 2 (adult-onset).
Gamadiabet
Pharmacology
Acetohexamide is an intermediate-acting, first-generation oral sulfonylurea. It lowers blood sugar by stimulating the pancreatic beta cells to secrete insulin and by helping the body use insulin efficiently. The pancreas must produce insulin for this medication to work. Acetohexamide has one-third the potency of chlorpropamide, and twice the potency of tolbutamide; however, similar hypoglycemic efficacy occurs with equipotent dosage of sulfonylureas.
Gamadiabet
Absorption
Rapidly absorbed from the GI tract.
Gamadiabet
side effects and Toxicity
Oral, rat LD50: 5 gm/kg; Oral, mouse LD50: >2500 mg/kg. Symptoms of an acetohexamide overdose include hunger, nausea, anxiety, cold sweats, weakness, drowsiness, unconsciousness, and coma.
Gamadiabet
Patient Information
No information avaliable
Gamadiabet
Organisms Affected
Humans and other mammals