Accupril en es it fr

Accupril Brand names, Accupril Analogs

Accupril Brand Names Mixture

  • No information avaliable

Accupril Chemical_Formula


Accupril RX_link

Accupril fda sheet

Accupril msds (material safety sheet)

Accupril Synthesis Reference

M. L. Hoefle, S. Klutchko, U.S. Pat. 4,344,949 (1982)

Accupril Molecular Weight

438.516 g/mol

Accupril Melting Point


Accupril H2O Solubility

1 mg/L

Accupril State


Accupril LogP


Accupril Dosage Forms


Accupril Indication

For the treatment of hypertension and chronic heart failure.

Accupril Pharmacology

Quinapril, an angiotensin-converting enzyme (ACE) inhibitor, is used to treat hypertension and heart failure. Like ramipril, quinapril is a prodrug that, upon deesterification, is converted to the active metabolite quinaprilat. The effect of quinapril in hypertension and in congestive heart failure (CHF) appears to result primarily from the inhibition of circulating and tissue ACE activity, thereby reducing angiotensin II formation.

Accupril Absorption

Following oral administration, peak plasma quinapril concentrations are observed within one hour. Based on recovery of quinapril and its metabolites in urine, the extent of absorption is at least 60%. The rate and extent of quinapril absorption are diminished moderately (approximately 25-30%) when ACCUPRIL tablets are administered during a high-fat meal.

Accupril side effects and Toxicity

Overdose may lead to severe hypotension. LD50=1739mg/kg (orally in mice).

Accupril Patient Information

Accupril Organisms Affected

Humans and other mammals