Quinapril Hcl en es it fr

Quinapril Hcl Brand names, Quinapril Hcl Analogs

Quinapril Hcl Brand Names Mixture

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Quinapril Hcl Chemical_Formula


Quinapril Hcl RX_link


Quinapril Hcl fda sheet

Quinapril Hcl msds (material safety sheet)

Quinapril Hcl Synthesis Reference

M. L. Hoefle, S. Klutchko, U.S. Pat. 4,344,949 (1982)

Quinapril Hcl Molecular Weight

438.516 g/mol

Quinapril Hcl Melting Point


Quinapril Hcl H2O Solubility

1 mg/L

Quinapril Hcl State


Quinapril Hcl LogP


Quinapril Hcl Dosage Forms


Quinapril Hcl Indication

For the treatment of hypertension and chronic heart failure.

Quinapril Hcl Pharmacology

Quinapril, an angiotensin-converting enzyme (ACE) inhibitor, is used to treat hypertension and heart failure. Like ramipril, quinapril is a prodrug that, upon deesterification, is converted to the active metabolite quinaprilat. The effect of quinapril in hypertension and in congestive heart failure (CHF) appears to result primarily from the inhibition of circulating and tissue ACE activity, thereby reducing angiotensin II formation.

Quinapril Hcl Absorption

Following oral administration, peak plasma quinapril concentrations are observed within one hour. Based on recovery of quinapril and its metabolites in urine, the extent of absorption is at least 60%. The rate and extent of quinapril absorption are diminished moderately (approximately 25-30%) when ACCUPRIL tablets are administered during a high-fat meal.

Quinapril Hcl side effects and Toxicity

Overdose may lead to severe hypotension. LD50=1739mg/kg (orally in mice).

Quinapril Hcl Patient Information

Quinapril Hcl Organisms Affected

Humans and other mammals