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Acequin Brand names, Acequin Analogs

Acequin Brand Names Mixture

  • No information avaliable

Acequin Chemical_Formula


Acequin RX_link

Acequin fda sheet

Acequin msds (material safety sheet)

Acequin Synthesis Reference

M. L. Hoefle, S. Klutchko, U.S. Pat. 4,344,949 (1982)

Acequin Molecular Weight

438.516 g/mol

Acequin Melting Point


Acequin H2O Solubility

1 mg/L

Acequin State


Acequin LogP


Acequin Dosage Forms


Acequin Indication

For the treatment of hypertension and chronic heart failure.

Acequin Pharmacology

Quinapril, an angiotensin-converting enzyme (ACE) inhibitor, is used to treat hypertension and heart failure. Like ramipril, quinapril is a prodrug that, upon deesterification, is converted to the active metabolite quinaprilat. The effect of quinapril in hypertension and in congestive heart failure (CHF) appears to result primarily from the inhibition of circulating and tissue ACE activity, thereby reducing angiotensin II formation.

Acequin Absorption

Following oral administration, peak plasma quinapril concentrations are observed within one hour. Based on recovery of quinapril and its metabolites in urine, the extent of absorption is at least 60%. The rate and extent of quinapril absorption are diminished moderately (approximately 25-30%) when ACCUPRIL tablets are administered during a high-fat meal.

Acequin side effects and Toxicity

Overdose may lead to severe hypotension. LD50=1739mg/kg (orally in mice).

Acequin Patient Information

Acequin Organisms Affected

Humans and other mammals