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Quinazil Brand names, Quinazil Analogs

Quinazil Brand Names Mixture

  • No information avaliable

Quinazil Chemical_Formula


Quinazil RX_link


Quinazil fda sheet

Quinazil msds (material safety sheet)

Quinazil Synthesis Reference

M. L. Hoefle, S. Klutchko, U.S. Pat. 4,344,949 (1982)

Quinazil Molecular Weight

438.516 g/mol

Quinazil Melting Point


Quinazil H2O Solubility

1 mg/L

Quinazil State


Quinazil LogP


Quinazil Dosage Forms


Quinazil Indication

For the treatment of hypertension and chronic heart failure.

Quinazil Pharmacology

Quinapril, an angiotensin-converting enzyme (ACE) inhibitor, is used to treat hypertension and heart failure. Like ramipril, quinapril is a prodrug that, upon deesterification, is converted to the active metabolite quinaprilat. The effect of quinapril in hypertension and in congestive heart failure (CHF) appears to result primarily from the inhibition of circulating and tissue ACE activity, thereby reducing angiotensin II formation.

Quinazil Absorption

Following oral administration, peak plasma quinapril concentrations are observed within one hour. Based on recovery of quinapril and its metabolites in urine, the extent of absorption is at least 60%. The rate and extent of quinapril absorption are diminished moderately (approximately 25-30%) when ACCUPRIL tablets are administered during a high-fat meal.

Quinazil side effects and Toxicity

Overdose may lead to severe hypotension. LD50=1739mg/kg (orally in mice).

Quinazil Patient Information

Quinazil Organisms Affected

Humans and other mammals