Quinaprilum [Latin] en es it fr

Quinaprilum [Latin] Brand names, Quinaprilum [Latin] Analogs

Quinaprilum [Latin] Brand Names Mixture

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Quinaprilum [Latin] Chemical_Formula


Quinaprilum [Latin] RX_link


Quinaprilum [Latin] fda sheet

Quinaprilum [Latin] msds (material safety sheet)

Quinaprilum [Latin] Synthesis Reference

M. L. Hoefle, S. Klutchko, U.S. Pat. 4,344,949 (1982)

Quinaprilum [Latin] Molecular Weight

438.516 g/mol

Quinaprilum [Latin] Melting Point


Quinaprilum [Latin] H2O Solubility

1 mg/L

Quinaprilum [Latin] State


Quinaprilum [Latin] LogP


Quinaprilum [Latin] Dosage Forms


Quinaprilum [Latin] Indication

For the treatment of hypertension and chronic heart failure.

Quinaprilum [Latin] Pharmacology

Quinapril, an angiotensin-converting enzyme (ACE) inhibitor, is used to treat hypertension and heart failure. Like ramipril, quinapril is a prodrug that, upon deesterification, is converted to the active metabolite quinaprilat. The effect of quinapril in hypertension and in congestive heart failure (CHF) appears to result primarily from the inhibition of circulating and tissue ACE activity, thereby reducing angiotensin II formation.

Quinaprilum [Latin] Absorption

Following oral administration, peak plasma quinapril concentrations are observed within one hour. Based on recovery of quinapril and its metabolites in urine, the extent of absorption is at least 60%. The rate and extent of quinapril absorption are diminished moderately (approximately 25-30%) when ACCUPRIL tablets are administered during a high-fat meal.

Quinaprilum [Latin] side effects and Toxicity

Overdose may lead to severe hypotension. LD50=1739mg/kg (orally in mice).

Quinaprilum [Latin] Patient Information

Quinaprilum [Latin] Organisms Affected

Humans and other mammals