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Korec Brand names, Korec Analogs

Korec Brand Names Mixture

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Korec Chemical_Formula


Korec RX_link


Korec fda sheet

Korec msds (material safety sheet)

Korec Synthesis Reference

M. L. Hoefle, S. Klutchko, U.S. Pat. 4,344,949 (1982)

Korec Molecular Weight

438.516 g/mol

Korec Melting Point


Korec H2O Solubility

1 mg/L

Korec State


Korec LogP


Korec Dosage Forms


Korec Indication

For the treatment of hypertension and chronic heart failure.

Korec Pharmacology

Quinapril, an angiotensin-converting enzyme (ACE) inhibitor, is used to treat hypertension and heart failure. Like ramipril, quinapril is a prodrug that, upon deesterification, is converted to the active metabolite quinaprilat. The effect of quinapril in hypertension and in congestive heart failure (CHF) appears to result primarily from the inhibition of circulating and tissue ACE activity, thereby reducing angiotensin II formation.

Korec Absorption

Following oral administration, peak plasma quinapril concentrations are observed within one hour. Based on recovery of quinapril and its metabolites in urine, the extent of absorption is at least 60%. The rate and extent of quinapril absorption are diminished moderately (approximately 25-30%) when ACCUPRIL tablets are administered during a high-fat meal.

Korec side effects and Toxicity

Overdose may lead to severe hypotension. LD50=1739mg/kg (orally in mice).

Korec Patient Information

Korec Organisms Affected

Humans and other mammals