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Acuitel Brand names, Acuitel Analogs

Acuitel Brand Names Mixture

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Acuitel Chemical_Formula


Acuitel RX_link

Acuitel fda sheet

Acuitel msds (material safety sheet)

Acuitel Synthesis Reference

M. L. Hoefle, S. Klutchko, U.S. Pat. 4,344,949 (1982)

Acuitel Molecular Weight

438.516 g/mol

Acuitel Melting Point


Acuitel H2O Solubility

1 mg/L

Acuitel State


Acuitel LogP


Acuitel Dosage Forms


Acuitel Indication

For the treatment of hypertension and chronic heart failure.

Acuitel Pharmacology

Quinapril, an angiotensin-converting enzyme (ACE) inhibitor, is used to treat hypertension and heart failure. Like ramipril, quinapril is a prodrug that, upon deesterification, is converted to the active metabolite quinaprilat. The effect of quinapril in hypertension and in congestive heart failure (CHF) appears to result primarily from the inhibition of circulating and tissue ACE activity, thereby reducing angiotensin II formation.

Acuitel Absorption

Following oral administration, peak plasma quinapril concentrations are observed within one hour. Based on recovery of quinapril and its metabolites in urine, the extent of absorption is at least 60%. The rate and extent of quinapril absorption are diminished moderately (approximately 25-30%) when ACCUPRIL tablets are administered during a high-fat meal.

Acuitel side effects and Toxicity

Overdose may lead to severe hypotension. LD50=1739mg/kg (orally in mice).

Acuitel Patient Information

Acuitel Organisms Affected

Humans and other mammals