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Accupro Brand names, Accupro Analogs

Accupro Brand Names Mixture

  • No information avaliable

Accupro Chemical_Formula


Accupro RX_link

Accupro fda sheet

Accupro msds (material safety sheet)

Accupro Synthesis Reference

M. L. Hoefle, S. Klutchko, U.S. Pat. 4,344,949 (1982)

Accupro Molecular Weight

438.516 g/mol

Accupro Melting Point


Accupro H2O Solubility

1 mg/L

Accupro State


Accupro LogP


Accupro Dosage Forms


Accupro Indication

For the treatment of hypertension and chronic heart failure.

Accupro Pharmacology

Quinapril, an angiotensin-converting enzyme (ACE) inhibitor, is used to treat hypertension and heart failure. Like ramipril, quinapril is a prodrug that, upon deesterification, is converted to the active metabolite quinaprilat. The effect of quinapril in hypertension and in congestive heart failure (CHF) appears to result primarily from the inhibition of circulating and tissue ACE activity, thereby reducing angiotensin II formation.

Accupro Absorption

Following oral administration, peak plasma quinapril concentrations are observed within one hour. Based on recovery of quinapril and its metabolites in urine, the extent of absorption is at least 60%. The rate and extent of quinapril absorption are diminished moderately (approximately 25-30%) when ACCUPRIL tablets are administered during a high-fat meal.

Accupro side effects and Toxicity

Overdose may lead to severe hypotension. LD50=1739mg/kg (orally in mice).

Accupro Patient Information

Accupro Organisms Affected

Humans and other mammals