Tranimul
Category
Tranimul Brand names, Tranimul Analogs
Tranimul Brand Names Mixture
Tranimul Chemical_Formula
C16H13ClN2O
Tranimul RX_link
http://www.rxlist.com/cgi/generic/diazepam.htm
Tranimul fda sheet
Tranimul msds (material safety sheet)
Tranimul Synthesis Reference
Reeder, Sternbach; U.S. Pat. 3,371,085 (1968)
Tranimul Molecular Weight
284.74 g/mol
Tranimul Melting Point
125-126oC
Tranimul H2O Solubility
Slightly soluble (50 mg/L)
Tranimul State
solid
Tranimul LogP
2.988
Tranimul Dosage Forms
Tablets; Injectable solution
Tranimul Indication
Used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and premedicant, as an anticonvulsant, and in the management of alcohol withdrawal syndrome.
Tranimul Pharmacology
Diazepam, a benzodiazepine, generates the same active metabolite as chlordiazepoxide and clorazepate. In animals, diazepam appears to act on parts of the limbic system, the thalamus and hypothalamus, and induces calming effects. Diazepam, unlike chlorpromazine and reserpine, has no demonstrable peripheral autonomic blocking action, nor does it produce extrapyramidal side effects; however, animals treated with diazepam do have a transient ataxia at higher doses. Diazepam was found to have transient cardiovascular depressor effects in dogs. Long-term experiments in rats revealed no disturbances of endocrine function. Injections into animals have produced localized irritation of tissue surrounding injection sites and some thickening of veins after intravenous use.
Tranimul Absorption
Essentially complete, with a bioavailability of 93%.
Tranimul side effects and Toxicity
Symptoms of overdose include somnolence, confusion, coma, and diminished reflexes. Respiration, pulse and blood pressure should be monitored.
Tranimul Patient Information
Tranimul Organisms Affected
Humans and other mammals
