Duksen

Duksen Brand names, Duksen Analogs

Duksen Brand Names Mixture

No information avaliable

Duksen Chemical_Formula

C₁₆H₁₃ClN₂O

Duksen RX_link

http://www.rxlist.com/cgi/generic/diazepam.htm

Duksen fda sheet

Duksen msds (material safety sheet)

Duksen MSDS

Duksen Synthesis Reference

Reeder, Sternbach; U.S. Pat. 3,371,085 (1968)

Duksen Molecular Weight

284.74 g/mol

Duksen Melting Point

125-126^oC

Duksen H₂O Solubility

Slightly soluble (50 mg/L)

Duksen State

solid

Duksen LogP

2.988

Duksen Dosage Forms

Tablets; Injectable solution

Duksen Indication

Used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and premedicant, as an anticonvulsant, and in the management of alcohol withdrawal syndrome.

Duksen Pharmacology

Diazepam, a benzodiazepine, generates the same active metabolite as chlordiazepoxide and clorazepate. In animals, diazepam appears to act on parts of the limbic system, the thalamus and hypothalamus, and induces calming effects. Diazepam, unlike chlorpromazine and reserpine, has no demonstrable peripheral autonomic blocking action, nor does it produce extrapyramidal side effects; however, animals treated with diazepam do have a transient ataxia at higher doses. Diazepam was found to have transient cardiovascular depressor effects in dogs. Long-term experiments in rats revealed no disturbances of endocrine function. Injections into animals have produced localized irritation of tissue surrounding injection sites and some thickening of veins after intravenous use.

Duksen Absorption

Essentially complete, with a bioavailability of 93%.

Duksen side effects and Toxicity

Symptoms of overdose include somnolence, confusion, coma, and diminished reflexes. Respiration, pulse and blood pressure should be monitored.

Duksen Patient Information

Duksen Organisms Affected

Humans and other mammals