Lembrol

Lembrol Brand names, Lembrol Analogs

Lembrol Brand Names Mixture

No information avaliable

Lembrol Chemical_Formula

C₁₆H₁₃ClN₂O

Lembrol RX_link

http://www.rxlist.com/cgi/generic/diazepam.htm

Lembrol fda sheet

Lembrol msds (material safety sheet)

Lembrol MSDS

Lembrol Synthesis Reference

Reeder, Sternbach; U.S. Pat. 3,371,085 (1968)

Lembrol Molecular Weight

284.74 g/mol

Lembrol Melting Point

125-126^oC

Lembrol H₂O Solubility

Slightly soluble (50 mg/L)

Lembrol State

solid

Lembrol LogP

2.988

Lembrol Dosage Forms

Tablets; Injectable solution

Lembrol Indication

Used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and premedicant, as an anticonvulsant, and in the management of alcohol withdrawal syndrome.

Lembrol Pharmacology

Diazepam, a benzodiazepine, generates the same active metabolite as chlordiazepoxide and clorazepate. In animals, diazepam appears to act on parts of the limbic system, the thalamus and hypothalamus, and induces calming effects. Diazepam, unlike chlorpromazine and reserpine, has no demonstrable peripheral autonomic blocking action, nor does it produce extrapyramidal side effects; however, animals treated with diazepam do have a transient ataxia at higher doses. Diazepam was found to have transient cardiovascular depressor effects in dogs. Long-term experiments in rats revealed no disturbances of endocrine function. Injections into animals have produced localized irritation of tissue surrounding injection sites and some thickening of veins after intravenous use.

Lembrol Absorption

Essentially complete, with a bioavailability of 93%.

Lembrol side effects and Toxicity

Symptoms of overdose include somnolence, confusion, coma, and diminished reflexes. Respiration, pulse and blood pressure should be monitored.

Lembrol Patient Information

Lembrol Organisms Affected

Humans and other mammals