Aliseum

Aliseum Brand names, Aliseum Analogs

Aliseum Brand Names Mixture

No information avaliable

Aliseum Chemical_Formula

C₁₆H₁₃ClN₂O

Aliseum RX_link

http://www.rxlist.com/cgi/generic/diazepam.htm

Aliseum fda sheet

Aliseum msds (material safety sheet)

Aliseum MSDS

Aliseum Synthesis Reference

Reeder, Sternbach; U.S. Pat. 3,371,085 (1968)

Aliseum Molecular Weight

284.74 g/mol

Aliseum Melting Point

125-126^oC

Aliseum H₂O Solubility

Slightly soluble (50 mg/L)

Aliseum State

solid

Aliseum LogP

2.988

Aliseum Dosage Forms

Tablets; Injectable solution

Aliseum Indication

Used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and premedicant, as an anticonvulsant, and in the management of alcohol withdrawal syndrome.

Aliseum Pharmacology

Diazepam, a benzodiazepine, generates the same active metabolite as chlordiazepoxide and clorazepate. In animals, diazepam appears to act on parts of the limbic system, the thalamus and hypothalamus, and induces calming effects. Diazepam, unlike chlorpromazine and reserpine, has no demonstrable peripheral autonomic blocking action, nor does it produce extrapyramidal side effects; however, animals treated with diazepam do have a transient ataxia at higher doses. Diazepam was found to have transient cardiovascular depressor effects in dogs. Long-term experiments in rats revealed no disturbances of endocrine function. Injections into animals have produced localized irritation of tissue surrounding injection sites and some thickening of veins after intravenous use.

Aliseum Absorption

Essentially complete, with a bioavailability of 93%.

Aliseum side effects and Toxicity

Symptoms of overdose include somnolence, confusion, coma, and diminished reflexes. Respiration, pulse and blood pressure should be monitored.

Aliseum Patient Information

Aliseum Organisms Affected

Humans and other mammals