Novazam

Novazam Brand names, Novazam Analogs

Novazam Brand Names Mixture

No information avaliable

Novazam Chemical_Formula

C₁₆H₁₃ClN₂O

Novazam RX_link

http://www.rxlist.com/cgi/generic/diazepam.htm

Novazam fda sheet

Novazam msds (material safety sheet)

Novazam MSDS

Novazam Synthesis Reference

Reeder, Sternbach; U.S. Pat. 3,371,085 (1968)

Novazam Molecular Weight

284.74 g/mol

Novazam Melting Point

125-126^oC

Novazam H₂O Solubility

Slightly soluble (50 mg/L)

Novazam State

solid

Novazam LogP

2.988

Novazam Dosage Forms

Tablets; Injectable solution

Novazam Indication

Used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and premedicant, as an anticonvulsant, and in the management of alcohol withdrawal syndrome.

Novazam Pharmacology

Diazepam, a benzodiazepine, generates the same active metabolite as chlordiazepoxide and clorazepate. In animals, diazepam appears to act on parts of the limbic system, the thalamus and hypothalamus, and induces calming effects. Diazepam, unlike chlorpromazine and reserpine, has no demonstrable peripheral autonomic blocking action, nor does it produce extrapyramidal side effects; however, animals treated with diazepam do have a transient ataxia at higher doses. Diazepam was found to have transient cardiovascular depressor effects in dogs. Long-term experiments in rats revealed no disturbances of endocrine function. Injections into animals have produced localized irritation of tissue surrounding injection sites and some thickening of veins after intravenous use.

Novazam Absorption

Essentially complete, with a bioavailability of 93%.

Novazam side effects and Toxicity

Symptoms of overdose include somnolence, confusion, coma, and diminished reflexes. Respiration, pulse and blood pressure should be monitored.

Novazam Patient Information

Novazam Organisms Affected

Humans and other mammals