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Apaurin Brand names, Apaurin Analogs

Apaurin Brand Names Mixture

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Apaurin Chemical_Formula


Apaurin RX_link


Apaurin fda sheet

Apaurin msds (material safety sheet)

Apaurin MSDS

Apaurin Synthesis Reference

Reeder, Sternbach; U.S. Pat. 3,371,085 (1968)

Apaurin Molecular Weight

284.74 g/mol

Apaurin Melting Point


Apaurin H2O Solubility

Slightly soluble (50 mg/L)

Apaurin State


Apaurin LogP


Apaurin Dosage Forms

Tablets; Injectable solution

Apaurin Indication

Used in the treatment of severe anxiety disorders, as a hypnotic in the short-term management of insomnia, as a sedative and premedicant, as an anticonvulsant, and in the management of alcohol withdrawal syndrome.

Apaurin Pharmacology

Diazepam, a benzodiazepine, generates the same active metabolite as chlordiazepoxide and clorazepate. In animals, diazepam appears to act on parts of the limbic system, the thalamus and hypothalamus, and induces calming effects. Diazepam, unlike chlorpromazine and reserpine, has no demonstrable peripheral autonomic blocking action, nor does it produce extrapyramidal side effects; however, animals treated with diazepam do have a transient ataxia at higher doses. Diazepam was found to have transient cardiovascular depressor effects in dogs. Long-term experiments in rats revealed no disturbances of endocrine function. Injections into animals have produced localized irritation of tissue surrounding injection sites and some thickening of veins after intravenous use.

Apaurin Absorption

Essentially complete, with a bioavailability of 93%.

Apaurin side effects and Toxicity

Symptoms of overdose include somnolence, confusion, coma, and diminished reflexes. Respiration, pulse and blood pressure should be monitored.

Apaurin Patient Information

Apaurin Organisms Affected

Humans and other mammals