Atamet
Categorie
Atamet Les marques, Atamet Analogs
Atamet Les marques melange
Atamet Formule chimique
C10H14N2O4
Atamet RX lien
http://www.rxlist.com/cgi/generic/sinemet.htm
Atamet FDA fiche
Atamet msds (fiche de securite des materiaux)
Atamet Synthese de reference
Chemerda et al., US. 3,462,536 (1963)
Atamet Poids moleculaire
226.229 g/mol
Atamet Point de fusion
203-205oC
Atamet H2O Solubilite
3,8 mg / L
Atamet Etat
Solid
Atamet LogP
0.494
Atamet Formes pharmaceutiques
Comprimé (25 mg)
Atamet Indication
Pour le traitement des symptômes de la maladie de Parkinson idiopathique (paralysie agitante), parkinsonisme post-encéphalitique
Atamet Pharmacologie
Carbidopa, un inhibiteur de la décarboxylase non compétitif, est utilisé en combinaison avec la lévodopa pour le traitement de la maladie de Parkinson.
Atamet Absorption
Rapidement décarboxylée à la dopamine dans les tissus extracérébrales sorte que seule une petite partie d'une dose donnée est transporté inchangées pour le système nerveux central.
Atamet Toxicite
Les symptômes d'une toxicité carbidopa comprendre des spasmes musculaires ou une faiblesse, des spasmes de la paupière, des nausées, des vomissements, des diarrhées, un rythme cardiaque irrégulier, confusion, agitation, hallucinations, et l'inconscience.
Atamet Information pour les patients
Carbidopa is used with levodopa to treat Parkinson's disease. Parkinson's disease
is believed to be related to low levels of a chemical called dopamine (DOE pa meen)
in the brain. Levodopa (Dopar, Larodopa) is turned into dopamine in the body.
Carbidopa is used with levodopa to prevent the breakdown (metabolism) of levodopa
before it can reach the brain and take effect. Carbidopa is only effective if it is
taken with levodopa. It has no effect if it is used alone. Carbidopa is used with
levodopa to treat the stiffness, tremors, spasms, and poor muscle control of
Parkinson's disease. These medications are also used to treat the same muscular
conditions when they are caused by drugs such as chlorpromazine (Thorazine),
fluphenazine (Prolixin), perphenazine (Trilafon), and others.
is believed to be related to low levels of a chemical called dopamine (DOE pa meen)
in the brain. Levodopa (Dopar, Larodopa) is turned into dopamine in the body.
Carbidopa is used with levodopa to prevent the breakdown (metabolism) of levodopa
before it can reach the brain and take effect. Carbidopa is only effective if it is
taken with levodopa. It has no effect if it is used alone. Carbidopa is used with
levodopa to treat the stiffness, tremors, spasms, and poor muscle control of
Parkinson's disease. These medications are also used to treat the same muscular
conditions when they are caused by drugs such as chlorpromazine (Thorazine),
fluphenazine (Prolixin), perphenazine (Trilafon), and others.
Atamet Organismes affectes
Les humains et autres mammifères
