Atamet
Categoria
Atamet Nombres de marca, Atamet Analogos
Atamet Marca los nombres de mezcla
Atamet Formula quimica
C10H14N2O4
Atamet RX enlace
http://www.rxlist.com/cgi/generic/sinemet.htm
Atamet FDA hoja
Atamet MSDS (hoja de seguridad de materiales)
Atamet Sintesis de referencia
Chemerda et al., Patente de EE.UU.. 3,462,536 (1963)
Atamet Peso molecular
226.229 g/mol
Atamet Punto de fusion
203-205oC
Atamet H2O Solubilidad
3,8 mg / L
Atamet Estado
Solid
Atamet LogP
0.494
Atamet Formas de dosificacion
Comprimido (25 mg)
Atamet Indicacion
Para el tratamiento de los síntomas de la enfermedad de Parkinson idiopática (parálisis agitante), parkinsonismo postencefalítico
Atamet Farmacologia
Carbidopa, un inhibidor de la descarboxilasa no competitivo, se utiliza en combinación con levodopa para el tratamiento de la enfermedad de Parkinson.
Atamet Absorcion
Descarboxila rápidamente en dopamina en los tejidos extracerebrales de modo que sólo una pequeña parte de la dosis administrada es transportado sin cambios en el sistema nervioso central.
Atamet Toxicidad
Los síntomas de una toxicidad carbidopa incluyen espasmos musculares o debilidad, espasmos de los párpados, náuseas, vómitos, diarrea, un latido irregular del corazón, confusión, agitación, alucinaciones y pérdida del conocimiento.
Atamet Informacion de Pacientes
Carbidopa is used with levodopa to treat Parkinson's disease. Parkinson's disease
is believed to be related to low levels of a chemical called dopamine (DOE pa meen)
in the brain. Levodopa (Dopar, Larodopa) is turned into dopamine in the body.
Carbidopa is used with levodopa to prevent the breakdown (metabolism) of levodopa
before it can reach the brain and take effect. Carbidopa is only effective if it is
taken with levodopa. It has no effect if it is used alone. Carbidopa is used with
levodopa to treat the stiffness, tremors, spasms, and poor muscle control of
Parkinson's disease. These medications are also used to treat the same muscular
conditions when they are caused by drugs such as chlorpromazine (Thorazine),
fluphenazine (Prolixin), perphenazine (Trilafon), and others.
is believed to be related to low levels of a chemical called dopamine (DOE pa meen)
in the brain. Levodopa (Dopar, Larodopa) is turned into dopamine in the body.
Carbidopa is used with levodopa to prevent the breakdown (metabolism) of levodopa
before it can reach the brain and take effect. Carbidopa is only effective if it is
taken with levodopa. It has no effect if it is used alone. Carbidopa is used with
levodopa to treat the stiffness, tremors, spasms, and poor muscle control of
Parkinson's disease. These medications are also used to treat the same muscular
conditions when they are caused by drugs such as chlorpromazine (Thorazine),
fluphenazine (Prolixin), perphenazine (Trilafon), and others.
Atamet Organismos afectados
Humanos y otros mamíferos
