Categoria
Dolly
Nombres de marca,
Dolly
Analogos
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Marca los nombres de mezcla
No information avaliable
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Formula quimica
C21H27NO
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RX enlace
http://www.rxlist.com/cgi/generic/methdone.htm
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FDA hoja
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MSDS (hoja de seguridad de materiales)
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Sintesis de referencia
No hay información disponible
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Peso molecular
309.445 g/mol
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Punto de fusion
235.0oC
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H2O Solubilidad
48.5 mg / L
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Estado
Solid
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LogP
5.458
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Formas de dosificacion
Tableta
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Indicacion
Para el tratamiento de la tos seca, síndrome de abstinencia de drogas, la dependencia de opioides tipo de drogas, y el dolor
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Farmacologia
La metadona es un analgésico opiáceo sintético con múltiples acciones cuantitativamente similares a los de la morfina, la de los más importantes que afectan al sistema nervioso central y órganos compuestos de suave muscular. Sin embargo, la metadona es más activo y más tóxica que la morfina. La metadona está indicado para el alivio del dolor severo, para el tratamiento de desintoxicación de la adicción a los narcóticos, y para el mantenimiento temporal tratamiento de la adicción a los narcóticos. Las principales acciones de valor terapéutico son la analgesia y la sedación y la desintoxicación o mantenimiento temporal de la adicción a los narcóticos. El síndrome de abstinencia con metadona, , Aunque cualitativamente similar al de la morfina, se diferencia en que el inicio es más lento, el curso es más prolongado, y los síntomas son menos severos.
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Absorcion
No hay información disponible
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Toxicidad
No hay información disponible
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Informacion de Pacientes
PATIENT INFORMATION
Narcotic analgesics are used to relieve pain. Some of these medicines are also used just before or during an operation to help the anesthetic work better. Codeine and hydrocodone are also used to relieve coughing. Methadone is also used to help some people control their dependence on heroin or other narcotics. Narcotic analgesics may also be used for other conditions as determined by your doctor.
Narcotic analgesics act in the central nervous system (CNS) to relieve pain. Some of their side effects are also caused by actions in the CNS.
If a narcotic is used for a long time, it may become habit-forming (causing mental or physical dependence). Physical dependence may lead to withdrawal side effects when you stop taking the medicine.
These medicines are available only with your medical doctor's or dentist's prescription. For some of them, prescriptions cannot be refilled and you must obtain a new prescription from your medical doctor or dentist each time you need the medicine. In addition, other rules and regulations may apply when methadone is used to treat narcotic dependence.
-Tell your doctor if you have ever had any unusual or allergic reaction to any of the narcotic analgesics. Also tell to your doctor if you are allergic to any other substances, such as foods, preservatives, or dyes.
-Too much use of a narcotic during pregnancy may cause the baby to become dependent on the medicine. This may lead to withdrawal side effects after birth. Also, some of these medicines may cause breathing problems in the newborn
infant if taken just before delivery.
-Most narcotic analgesics have not been reported to cause problems in nursing babies. However, when the mother is taking large amounts of methadone (in a methadone maintenance program), the nursing baby may become dependent on the medicine. Also, butorphanol, codeine, meperidine, morphine, opium, and propoxyphene pass into the breast milk.
-Breathing problems may be especially likely to occur in children younger than 2 years of age. These children are usually more sensitive than adults to the effects of narcotic analgesics. Also, unusual excitement or restlessness may be more likely to occur in children receiving these medicines.
-Elderly people are especially sensitive to the effects of narcotic analgesics. This may increase the chance of side effects, especially breathing problems, during treatment.
-Methadone should be used with caution and in reduced dosage in patients who are concurrently receiving other narcotic analgesics, general anesthetics, phenothiazines, other tranquilizers, sedative-hypnotics, tricyclic antidepressants, and other CNS depressants (including alcohol). Respiratory depression, hypotension, and profound sedation or coma may result.
-Read more about Methadone on:
http://www.rxlist.com/cgi/generic/methdone_wcp.htm
http://www.drugs.com/cons/Methadone.html
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Organismos afectados
Humanos y otros mamíferos