Xi-Disopyramide
Brand names,
Xi-Disopyramide
Analogs
Xi-Disopyramide
Brand Names Mixture
Xi-Disopyramide
Chemical_Formula
C21H29N3O
Xi-Disopyramide
RX_link
http://www.rxlist.com/cgi/generic2/disopyr.htm
Xi-Disopyramide
fda sheet
Xi-Disopyramide
msds (material safety sheet)
Xi-Disopyramide
Synthesis Reference
No information avaliable
Xi-Disopyramide
Molecular Weight
339.475 g/mol
Xi-Disopyramide
Melting Point
94.5-95 oC
Xi-Disopyramide
H2O Solubility
44.9 mg/L
Xi-Disopyramide
State
Solid
Xi-Disopyramide
LogP
3.972
Xi-Disopyramide
Dosage Forms
Capsule; Tablet (extended-release)
Xi-Disopyramide
Indication
For the treatment of documented ventricular arrhythmias, such as sustained ventricular tachycardia, ventricular pre-excitation and cardiac dysrhythmias.
Xi-Disopyramide
Pharmacology
Disopyramide is an antiarrhythmic drug indicated for the treatment of documented ventricular arrhythmias, such as sustained ventricular tachycardia that are life-threatening. In man, Disopyramide at therapeutic plasma levels shortens the sinus node recovery time, lengthens the effective refractory period of the atrium, and has a minimal effect on the effective refractory period of the AV node. Little effect has been shown on AV-nodal and His-Purkinje conduction times or QRS duration. However, prolongation of conduction in accessory pathways occurs.
Xi-Disopyramide
Absorption
Nearly complete
Xi-Disopyramide
side effects and Toxicity
LD50=580 mg/kg in rats
Xi-Disopyramide
Patient Information
No information avaliable
Xi-Disopyramide
Organisms Affected
Humans and other mammals