Searle 703
Searle 703 Brand names, Searle 703 Analogs
Searle 703 Brand Names Mixture
- No information avaliable
Searle 703 Chemical_Formula
C21H29N3O
Searle 703 RX_link
http://www.rxlist.com/cgi/generic2/disopyr.htm
Searle 703 fda sheet
Searle 703 msds (material safety sheet)
Searle 703 Synthesis Reference
No information avaliable
Searle 703 Molecular Weight
339.475 g/mol
Searle 703 Melting Point
94.5-95 oC
Searle 703 H2O Solubility
44.9 mg/L
Searle 703 State
Solid
Searle 703 LogP
3.972
Searle 703 Dosage Forms
Capsule; Tablet (extended-release)
Searle 703 Indication
For the treatment of documented ventricular arrhythmias, such as sustained ventricular tachycardia, ventricular pre-excitation and cardiac dysrhythmias.
Searle 703 Pharmacology
Disopyramide is an antiarrhythmic drug indicated for the treatment of documented ventricular arrhythmias, such as sustained ventricular tachycardia that are life-threatening. In man, Disopyramide at therapeutic plasma levels shortens the sinus node recovery time, lengthens the effective refractory period of the atrium, and has a minimal effect on the effective refractory period of the AV node. Little effect has been shown on AV-nodal and His-Purkinje conduction times or QRS duration. However, prolongation of conduction in accessory pathways occurs.
Searle 703 Absorption
Nearly complete
Searle 703 side effects and Toxicity
LD50=580 mg/kg in rats
Searle 703 Patient Information
No information avaliable
Searle 703 Organisms Affected
Humans and other mammals
