Searle 703

Searle 703 Brand names, Searle 703 Analogs

Searle 703 Brand Names Mixture

No information avaliable

Searle 703 Chemical_Formula

C₂₁H₂₉N₃O

Searle 703 RX_link

http://www.rxlist.com/cgi/generic2/disopyr.htm

Searle 703 fda sheet

Searle 703 msds (material safety sheet)

Searle 703 Synthesis Reference

No information avaliable

Searle 703 Molecular Weight

339.475 g/mol

Searle 703 Melting Point

94.5-95 ^oC

Searle 703 H₂O Solubility

44.9 mg/L

Searle 703 State

Solid

Searle 703 LogP

3.972

Searle 703 Dosage Forms

Capsule; Tablet (extended-release)

Searle 703 Indication

For the treatment of documented ventricular arrhythmias, such as sustained ventricular tachycardia, ventricular pre-excitation and cardiac dysrhythmias.

Searle 703 Pharmacology

Disopyramide is an antiarrhythmic drug indicated for the treatment of documented ventricular arrhythmias, such as sustained ventricular tachycardia that are life-threatening. In man, Disopyramide at therapeutic plasma levels shortens the sinus node recovery time, lengthens the effective refractory period of the atrium, and has a minimal effect on the effective refractory period of the AV node. Little effect has been shown on AV-nodal and His-Purkinje conduction times or QRS duration. However, prolongation of conduction in accessory pathways occurs.

Searle 703 Absorption

Nearly complete

Searle 703 side effects and Toxicity

LD₅₀=580 mg/kg in rats

Searle 703 Patient Information