Lispine

Lispine Brand names, Lispine Analogs

Lispine Brand Names Mixture

No information avaliable

Lispine Chemical_Formula

C₂₁H₂₉N₃O

Lispine RX_link

http://www.rxlist.com/cgi/generic2/disopyr.htm

Lispine fda sheet

Lispine msds (material safety sheet)

Lispine Synthesis Reference

No information avaliable

Lispine Molecular Weight

339.475 g/mol

Lispine Melting Point

94.5-95 ^oC

Lispine H₂O Solubility

44.9 mg/L

Lispine State

Solid

Lispine LogP

3.972

Lispine Dosage Forms

Capsule; Tablet (extended-release)

Lispine Indication

For the treatment of documented ventricular arrhythmias, such as sustained ventricular tachycardia, ventricular pre-excitation and cardiac dysrhythmias.

Lispine Pharmacology

Disopyramide is an antiarrhythmic drug indicated for the treatment of documented ventricular arrhythmias, such as sustained ventricular tachycardia that are life-threatening. In man, Disopyramide at therapeutic plasma levels shortens the sinus node recovery time, lengthens the effective refractory period of the atrium, and has a minimal effect on the effective refractory period of the AV node. Little effect has been shown on AV-nodal and His-Purkinje conduction times or QRS duration. However, prolongation of conduction in accessory pathways occurs.

Lispine Absorption

Nearly complete

Lispine side effects and Toxicity

LD₅₀=580 mg/kg in rats

Lispine Patient Information