Rythmodan P
Brand names,
Rythmodan P
Analogs
Rythmodan P
Brand Names Mixture
Rythmodan P
Chemical_Formula
C21H29N3O
Rythmodan P
RX_link
http://www.rxlist.com/cgi/generic2/disopyr.htm
Rythmodan P
fda sheet
Rythmodan P
msds (material safety sheet)
Rythmodan P
Synthesis Reference
No information avaliable
Rythmodan P
Molecular Weight
339.475 g/mol
Rythmodan P
Melting Point
94.5-95 oC
Rythmodan P
H2O Solubility
44.9 mg/L
Rythmodan P
State
Solid
Rythmodan P
LogP
3.972
Rythmodan P
Dosage Forms
Capsule; Tablet (extended-release)
Rythmodan P
Indication
For the treatment of documented ventricular arrhythmias, such as sustained ventricular tachycardia, ventricular pre-excitation and cardiac dysrhythmias.
Rythmodan P
Pharmacology
Disopyramide is an antiarrhythmic drug indicated for the treatment of documented ventricular arrhythmias, such as sustained ventricular tachycardia that are life-threatening. In man, Disopyramide at therapeutic plasma levels shortens the sinus node recovery time, lengthens the effective refractory period of the atrium, and has a minimal effect on the effective refractory period of the AV node. Little effect has been shown on AV-nodal and His-Purkinje conduction times or QRS duration. However, prolongation of conduction in accessory pathways occurs.
Rythmodan P
Absorption
Nearly complete
Rythmodan P
side effects and Toxicity
LD50=580 mg/kg in rats
Rythmodan P
Patient Information
No information avaliable
Rythmodan P
Organisms Affected
Humans and other mammals