Disopyramide Free Base
Brand names,
Disopyramide Free Base
Analogs
Disopyramide Free Base
Brand Names Mixture
Disopyramide Free Base
Chemical_Formula
C21H29N3O
Disopyramide Free Base
RX_link
http://www.rxlist.com/cgi/generic2/disopyr.htm
Disopyramide Free Base
fda sheet
Disopyramide Free Base
msds (material safety sheet)
Disopyramide Free Base
Synthesis Reference
No information avaliable
Disopyramide Free Base
Molecular Weight
339.475 g/mol
Disopyramide Free Base
Melting Point
94.5-95 oC
Disopyramide Free Base
H2O Solubility
44.9 mg/L
Disopyramide Free Base
State
Solid
Disopyramide Free Base
LogP
3.972
Disopyramide Free Base
Dosage Forms
Capsule; Tablet (extended-release)
Disopyramide Free Base
Indication
For the treatment of documented ventricular arrhythmias, such as sustained ventricular tachycardia, ventricular pre-excitation and cardiac dysrhythmias.
Disopyramide Free Base
Pharmacology
Disopyramide is an antiarrhythmic drug indicated for the treatment of documented ventricular arrhythmias, such as sustained ventricular tachycardia that are life-threatening. In man, Disopyramide at therapeutic plasma levels shortens the sinus node recovery time, lengthens the effective refractory period of the atrium, and has a minimal effect on the effective refractory period of the AV node. Little effect has been shown on AV-nodal and His-Purkinje conduction times or QRS duration. However, prolongation of conduction in accessory pathways occurs.
Disopyramide Free Base
Absorption
Nearly complete
Disopyramide Free Base
side effects and Toxicity
LD50=580 mg/kg in rats
Disopyramide Free Base
Patient Information
No information avaliable
Disopyramide Free Base
Organisms Affected
Humans and other mammals