Disopyramidum [Inn-Latin]

Disopyramidum [Inn-Latin] Brand names, Disopyramidum [Inn-Latin] Analogs

Disopyramidum [Inn-Latin] Brand Names Mixture

No information avaliable

Disopyramidum [Inn-Latin] Chemical_Formula

C₂₁H₂₉N₃O

Disopyramidum [Inn-Latin] RX_link

http://www.rxlist.com/cgi/generic2/disopyr.htm

Disopyramidum [Inn-Latin] fda sheet

Disopyramidum [Inn-Latin] msds (material safety sheet)

Disopyramidum [Inn-Latin] Synthesis Reference

No information avaliable

Disopyramidum [Inn-Latin] Molecular Weight

339.475 g/mol

Disopyramidum [Inn-Latin] Melting Point

94.5-95 ^oC

Disopyramidum [Inn-Latin] H₂O Solubility

44.9 mg/L

Disopyramidum [Inn-Latin] State

Solid

Disopyramidum [Inn-Latin] LogP

3.972

Disopyramidum [Inn-Latin] Dosage Forms

Capsule; Tablet (extended-release)

Disopyramidum [Inn-Latin] Indication

For the treatment of documented ventricular arrhythmias, such as sustained ventricular tachycardia, ventricular pre-excitation and cardiac dysrhythmias.

Disopyramidum [Inn-Latin] Pharmacology

Disopyramide is an antiarrhythmic drug indicated for the treatment of documented ventricular arrhythmias, such as sustained ventricular tachycardia that are life-threatening. In man, Disopyramide at therapeutic plasma levels shortens the sinus node recovery time, lengthens the effective refractory period of the atrium, and has a minimal effect on the effective refractory period of the AV node. Little effect has been shown on AV-nodal and His-Purkinje conduction times or QRS duration. However, prolongation of conduction in accessory pathways occurs.

Disopyramidum [Inn-Latin] Absorption

Nearly complete

Disopyramidum [Inn-Latin] side effects and Toxicity

LD₅₀=580 mg/kg in rats

Disopyramidum [Inn-Latin] Patient Information