Norpace

Norpace Brand names, Norpace Analogs

Norpace Brand Names Mixture

No information avaliable

Norpace Chemical_Formula

C₂₁H₂₉N₃O

Norpace RX_link

http://www.rxlist.com/cgi/generic2/disopyr.htm

Norpace fda sheet

Norpace msds (material safety sheet)

Norpace Synthesis Reference

No information avaliable

Norpace Molecular Weight

339.475 g/mol

Norpace Melting Point

94.5-95 ^oC

Norpace H₂O Solubility

44.9 mg/L

Norpace State

Solid

Norpace LogP

3.972

Norpace Dosage Forms

Capsule; Tablet (extended-release)

Norpace Indication

For the treatment of documented ventricular arrhythmias, such as sustained ventricular tachycardia, ventricular pre-excitation and cardiac dysrhythmias.

Norpace Pharmacology

Disopyramide is an antiarrhythmic drug indicated for the treatment of documented ventricular arrhythmias, such as sustained ventricular tachycardia that are life-threatening. In man, Disopyramide at therapeutic plasma levels shortens the sinus node recovery time, lengthens the effective refractory period of the atrium, and has a minimal effect on the effective refractory period of the AV node. Little effect has been shown on AV-nodal and His-Purkinje conduction times or QRS duration. However, prolongation of conduction in accessory pathways occurs.

Norpace Absorption

Nearly complete

Norpace side effects and Toxicity

LD₅₀=580 mg/kg in rats

Norpace Patient Information