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Tramadol Brand names, Tramadol Analogs

Tramadol Brand Names Mixture

  • No information avaliable

Tramadol Chemical_Formula


Tramadol RX_link

Tramadol fda sheet

Tramadol FDA

Tramadol msds (material safety sheet)

Tramadol MSDS

Tramadol Synthesis Reference

K. Flick, E. Frankus, U.S. Pat 3,652,589 (1965)

Tramadol Molecular Weight

263.375 g/mol

Tramadol Melting Point


Tramadol H2O Solubility

Soluble in water.

Tramadol State


Tramadol LogP


Tramadol Dosage Forms


Tramadol Indication

Indicated in the treatment of moderate to severe pain.

Tramadol Pharmacology

Tramadol, a centrally-acting analgesic, exists as a racemic mixture of the trans isomer, with important differences in binding, activity, and metabolism associated with the two enantiomers. Although Tramadol is a synthetic analog of codeine, it has a significantly lower affinity for opioid receptors than codeine. Tramadol is used to treat postoperative, dental, cancer, and acute musculosketetal pain and as an adjuvant to NSAID therapy in patients with osteoarthritis.

Tramadol Absorption

Racemic tramadol is rapidly and almost completely absorbed after oral administration. The mean absolute bioavailability of a 100 mg oral dose is approximately 75%.The mean peak plasma concentration of racemic tramadol and M1 occurs at two and three hours, respectively, after administration in healthy adults.

Tramadol side effects and Toxicity

LD50=350mg/kg (orally in mice)

Tramadol Patient Information

No information avaliable

Tramadol Organisms Affected

Humans and other mammals