Ultram
Ultram Brand names, Ultram Analogs
Ultram Brand Names Mixture
- No information avaliable
Ultram Chemical_Formula
C16H25NO2
Ultram RX_link
http://www.rxlist.com/cgi/generic/tramadol.htm
Ultram fda sheet
Ultram msds (material safety sheet)
Ultram Synthesis Reference
K. Flick, E. Frankus, U.S. Pat 3,652,589 (1965)
Ultram Molecular Weight
263.375 g/mol
Ultram Melting Point
180-181oC
Ultram H2O Solubility
Soluble in water.
Ultram State
Solid
Ultram LogP
2.951
Ultram Dosage Forms
Tablet
Ultram Indication
Indicated in the treatment of moderate to severe pain.
Ultram Pharmacology
Tramadol, a centrally-acting analgesic, exists as a racemic mixture of the trans isomer, with important differences in binding, activity, and metabolism associated with the two enantiomers. Although Tramadol is a synthetic analog of codeine, it has a significantly lower affinity for opioid receptors than codeine. Tramadol is used to treat postoperative, dental, cancer, and acute musculosketetal pain and as an adjuvant to NSAID therapy in patients with osteoarthritis.
Ultram Absorption
Racemic tramadol is rapidly and almost completely absorbed after oral administration. The mean absolute bioavailability of a 100 mg oral dose is approximately 75%.The mean peak plasma concentration of racemic tramadol and M1 occurs at two and three hours, respectively, after administration in healthy adults.
Ultram side effects and Toxicity
LD50=350mg/kg (orally in mice)
Ultram Patient Information
No information avaliable
Ultram Organisms Affected
Humans and other mammals
