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Zydol Brand names, Zydol Analogs

Zydol Brand Names Mixture

  • No information avaliable

Zydol Chemical_Formula


Zydol RX_link


Zydol fda sheet

Zydol FDA

Zydol msds (material safety sheet)

Zydol MSDS

Zydol Synthesis Reference

K. Flick, E. Frankus, U.S. Pat 3,652,589 (1965)

Zydol Molecular Weight

263.375 g/mol

Zydol Melting Point


Zydol H2O Solubility

Soluble in water.

Zydol State


Zydol LogP


Zydol Dosage Forms


Zydol Indication

Indicated in the treatment of moderate to severe pain.

Zydol Pharmacology

Tramadol, a centrally-acting analgesic, exists as a racemic mixture of the trans isomer, with important differences in binding, activity, and metabolism associated with the two enantiomers. Although Tramadol is a synthetic analog of codeine, it has a significantly lower affinity for opioid receptors than codeine. Tramadol is used to treat postoperative, dental, cancer, and acute musculosketetal pain and as an adjuvant to NSAID therapy in patients with osteoarthritis.

Zydol Absorption

Racemic tramadol is rapidly and almost completely absorbed after oral administration. The mean absolute bioavailability of a 100 mg oral dose is approximately 75%.The mean peak plasma concentration of racemic tramadol and M1 occurs at two and three hours, respectively, after administration in healthy adults.

Zydol side effects and Toxicity

LD50=350mg/kg (orally in mice)

Zydol Patient Information

No information avaliable

Zydol Organisms Affected

Humans and other mammals