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Crispin Brand names, Crispin Analogs

Crispin Brand Names Mixture

  • No information avaliable

Crispin Chemical_Formula


Crispin RX_link

Crispin fda sheet

Crispin FDA

Crispin msds (material safety sheet)

Crispin MSDS

Crispin Synthesis Reference

K. Flick, E. Frankus, U.S. Pat 3,652,589 (1965)

Crispin Molecular Weight

263.375 g/mol

Crispin Melting Point


Crispin H2O Solubility

Soluble in water.

Crispin State


Crispin LogP


Crispin Dosage Forms


Crispin Indication

Indicated in the treatment of moderate to severe pain.

Crispin Pharmacology

Tramadol, a centrally-acting analgesic, exists as a racemic mixture of the trans isomer, with important differences in binding, activity, and metabolism associated with the two enantiomers. Although Tramadol is a synthetic analog of codeine, it has a significantly lower affinity for opioid receptors than codeine. Tramadol is used to treat postoperative, dental, cancer, and acute musculosketetal pain and as an adjuvant to NSAID therapy in patients with osteoarthritis.

Crispin Absorption

Racemic tramadol is rapidly and almost completely absorbed after oral administration. The mean absolute bioavailability of a 100 mg oral dose is approximately 75%.The mean peak plasma concentration of racemic tramadol and M1 occurs at two and three hours, respectively, after administration in healthy adults.

Crispin side effects and Toxicity

LD50=350mg/kg (orally in mice)

Crispin Patient Information

No information avaliable

Crispin Organisms Affected

Humans and other mammals