Tramadol HCl en es it fr

Tramadol HCl Brand names, Tramadol HCl Analogs

Tramadol HCl Brand Names Mixture

  • No information avaliable

Tramadol HCl Chemical_Formula


Tramadol HCl RX_link

Tramadol HCl fda sheet

Tramadol_HCl FDA

Tramadol HCl msds (material safety sheet)

Tramadol_HCl MSDS

Tramadol HCl Synthesis Reference

K. Flick, E. Frankus, U.S. Pat 3,652,589 (1965)

Tramadol HCl Molecular Weight

263.375 g/mol

Tramadol HCl Melting Point


Tramadol HCl H2O Solubility

Soluble in water.

Tramadol HCl State


Tramadol HCl LogP


Tramadol HCl Dosage Forms


Tramadol HCl Indication

Indicated in the treatment of moderate to severe pain.

Tramadol HCl Pharmacology

Tramadol, a centrally-acting analgesic, exists as a racemic mixture of the trans isomer, with important differences in binding, activity, and metabolism associated with the two enantiomers. Although Tramadol is a synthetic analog of codeine, it has a significantly lower affinity for opioid receptors than codeine. Tramadol is used to treat postoperative, dental, cancer, and acute musculosketetal pain and as an adjuvant to NSAID therapy in patients with osteoarthritis.

Tramadol HCl Absorption

Racemic tramadol is rapidly and almost completely absorbed after oral administration. The mean absolute bioavailability of a 100 mg oral dose is approximately 75%.The mean peak plasma concentration of racemic tramadol and M1 occurs at two and three hours, respectively, after administration in healthy adults.

Tramadol HCl side effects and Toxicity

LD50=350mg/kg (orally in mice)

Tramadol HCl Patient Information

No information avaliable

Tramadol HCl Organisms Affected

Humans and other mammals