Ralivia ER
Ralivia ER Brand names, Ralivia ER Analogs
Ralivia ER Brand Names Mixture
- No information avaliable
Ralivia ER Chemical_Formula
C16H25NO2
Ralivia ER RX_link
http://www.rxlist.com/cgi/generic/tramadol.htm
Ralivia ER fda sheet
Ralivia ER msds (material safety sheet)
Ralivia ER Synthesis Reference
K. Flick, E. Frankus, U.S. Pat 3,652,589 (1965)
Ralivia ER Molecular Weight
263.375 g/mol
Ralivia ER Melting Point
180-181oC
Ralivia ER H2O Solubility
Soluble in water.
Ralivia ER State
Solid
Ralivia ER LogP
2.951
Ralivia ER Dosage Forms
Tablet
Ralivia ER Indication
Indicated in the treatment of moderate to severe pain.
Ralivia ER Pharmacology
Tramadol, a centrally-acting analgesic, exists as a racemic mixture of the trans isomer, with important differences in binding, activity, and metabolism associated with the two enantiomers. Although Tramadol is a synthetic analog of codeine, it has a significantly lower affinity for opioid receptors than codeine. Tramadol is used to treat postoperative, dental, cancer, and acute musculosketetal pain and as an adjuvant to NSAID therapy in patients with osteoarthritis.
Ralivia ER Absorption
Racemic tramadol is rapidly and almost completely absorbed after oral administration. The mean absolute bioavailability of a 100 mg oral dose is approximately 75%.The mean peak plasma concentration of racemic tramadol and M1 occurs at two and three hours, respectively, after administration in healthy adults.
Ralivia ER side effects and Toxicity
LD50=350mg/kg (orally in mice)
Ralivia ER Patient Information
No information avaliable
Ralivia ER Organisms Affected
Humans and other mammals
